Chemistry: molecular biology and microbiology – Process of utilizing an enzyme or micro-organism to destroy... – Resolution of optical isomers or purification of organic...
Reexamination Certificate
2003-12-08
2010-02-23
Saucier, Sandra E (Department: 1651)
Chemistry: molecular biology and microbiology
Process of utilizing an enzyme or micro-organism to destroy...
Resolution of optical isomers or purification of organic...
Reexamination Certificate
active
07666659
ABSTRACT:
The present invention is to provide a process for simply producing an optically active 3-hydroxypropionic ester derivative useful as a medicament intermediate from an inexpensive material. More specifically, the present invention is directed to a process for producing an optically active 3-hydroxypropionic ester derivative comprising reacting an acetic ester derivative available at low cost with a base and a formic ester, thereby converting the acetic ester derivative into a 2-formylacetic ester derivative, and thereafter, stereospecifically reducing the formyl group of the derivative by use of an enzymatic source capable of stereoselectively reducing the formyl group of the derivative.
REFERENCES:
patent: 4734367 (1988-03-01), Leuenberger et al.
patent: 0 212 859 (1987-03-01), None
patent: 03-285689 (1991-12-01), None
Barth et al., “Physiology and genetics of the dimorphic fungus Yarrowia lipolytica”, FEMS Microbiology Reviews 19 : 219-237 (1997).
ATCC Bacteria and Bacteriophages, 19thEdition, p. 304 (1996).
Kido et al., “New Access to dl-Paniculide A Using α-PhenylthioVinylbutenolide as Synthetic Block”, Tetrahedron 43 (23) : 5467-5474 (1987).
Mori Kohei
Moriyama Daisuke
Oishi Takahiro
Taoka Naoaki
Kaneka Corporation
Saucier Sandra E
Sughrue & Mion, PLLC
LandOfFree
Process for producing optically active 3-hydroxypropionic... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for producing optically active 3-hydroxypropionic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for producing optically active 3-hydroxypropionic... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4173986