Chemistry: molecular biology and microbiology – Process of utilizing an enzyme or micro-organism to destroy... – Resolution of optical isomers or purification of organic...
Reexamination Certificate
2006-03-21
2006-03-21
Prats, Francisco (Department: 1651)
Chemistry: molecular biology and microbiology
Process of utilizing an enzyme or micro-organism to destroy...
Resolution of optical isomers or purification of organic...
C435S106000, C435S120000
Reexamination Certificate
active
07015029
ABSTRACT:
There is provided a novel method for producing an optically active (4R)-1,3-thiazolidine-4-carboxylic acid by allowing cells of a microorganism or a preparation obtained from cells of a microorganism having activity for stereoselectively hydrolyzing an optically active (4R)-1,3-thiazolidine-4-carboxylic acid amide to act on a mixture of (4R)- and (4S)-enantiomers of a 1,3-thiazolidine-4-carboxylic acid amide to produce the optically active (4R)-1,3-thiazolidine-4-carboxylic acid and separating the optically active (4R)-1,3-thiazolidine-4-carboxylic acid.
REFERENCES:
patent: 344 044 (1989-11-01), None
patent: 494 716 (1992-07-01), None
patent: 574 135 (1993-12-01), None
International Search Report—priority International Application No. PCT/JP01/10861; search completion date—Feb. 15, 2002.
Kallen, “The Mechanism of Reactions Involving Schiff Base Intermediates. Thiazolidine Formation from L-Cysteine and Formaldehyde,”Journal of the American Chemical Society,vol. 93, No. 23, pp. 6236-6248, Nov. 17, 1971.
Supplementary European Search Report completed Apr. 2, 2004 and issued to a pending foreign, related application.
Kato Takahiro
Kondo Toshio
Nakamura Go
Tamura Yutaka
Knobbe Martens Olson & Bear LLP
Mitsubishi Gas Chemical Co, Inc.
Prats Francisco
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