Process for producing optically active 1-substituted-1,3-propane

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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568862, 556 21, C07C 2914, C07C 2704

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active

053248708

ABSTRACT:
A process for producing an optically active 1-substituted-1,3-propanediol is disclosed, comprising hydrogenating a 3-substituted-3-oxopropanol or 3-substituted-3-oxopropanal in the presence of a ruthenium-phosphine complex represented by formula (I):

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J. Chem. Soc., Chem. Commun., 1985, 922-924.
J. Org. Chem., 1988, 53, 4081-4084.

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