Process for producing optically active 1,3-butanediol by asymmet

Details Process for producing optically active 1,3-butanediol by asymmet Process for producing optically active 1,3-butanediol by asymmet

1992-10-21

1995-03-28

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Resolution of optical isomers or purification of organic...

435822, 435911, C12P 4100

Patent

active

054016606

ABSTRACT:
An optically active 1,3-butanediol can be produced by either (1) treating a mixture of 1,3-butanediol enantiomers with a microorganism, which has been optionally treated, capable of asymmetrically assimilating said mixture, or (2) preparing a microorganism, which has been optionally treated, capable of asymmetrically reducing 4-hydroxy-2-butanone, and collecting optically active 1,3-butanediol.

REFERENCES:
Levene et al., J. Biol. Chem., 94, pp. 361-366, (1931).
Neuberg et al., Biochem. Z., 92, pp. 96-110 (1918).
Murakami et al., Bulletin of the Chemical Society of Japan, vol. 53, No. 5, pp. 1356-1360, (1980).

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