Process for producing nucleosides

Details Process for producing nucleosides Process for producing nucleosides

1994-10-07

1996-04-09

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 88, 435 89, 435193, 435194, 43525231, 4352525, C12N 912, C12P 1938

Patent

active

055061222

ABSTRACT:
The present invention concerns a process for producing nucleosides by carrying out the reaction of a base donor, a saccharide residue donor and a phosphoric acid donor by the use of an enzyme preparation containing nucleoside phosphorylase, thereby forming an N-glycosidic bond between the base moiety of the base donor and the saccharide moiety of the saccharide residue donor, which comprises using, as the enzyme preparation containing nucleoside phosphorylase, a preparation derived from the cells of one or more kinds of microorganisms belonging to thermophiles of the genus Bacillus and having high nucleoside phosphorylase activity per unit cell weight.

REFERENCES:
patent: 4331762 (1982-05-01), Nakajima et al.
patent: 4458016 (1984-07-01), Yamanaka et al.
patent: 4594321 (1986-06-01), Fujishima et al.
patent: 4614719 (1986-09-01), Fujishima et al.
patent: 5258301 (1993-11-01), Yamauchi et al.
patent: 5306629 (1994-04-01), Yamamoto et al.
patent: 5384251 (1995-01-01), Yamauchi et al.
HORI et al., "Synthesis of 5-Methyluridine by a Thermophile, Bacillus stearothermophilus JTS 859", Agric. Biol. Chem., 53(1), 197-202, 1989.
SAUNDERS et al., "Purification and Comparative Properties of a Pyrimidine Nucleoside Phosphorylase from Bacillus stearothermophilus", Journal of Biological Chemistry, vol. 244, No. 13, Jul. 10, 1969, pp. 3691-3697.
Nakashima et al., Patent Abstracts of Japan 56-148289 (Nov. 1981).
Saunders et al., Chemical Abstracts 56941r (1969).
JPO ABS (J 56-8676) ABS Pub. Apr. 21, 1981, UDAGAWA et al.
JPO ABS (J 61-104795) ABS Pub. Sep. 3, 1986, Tsunemi et al.
JPO ABS (J 60-239495) ABS Pub. Apr. 25, 1986, Kobayashi et al.

Affiliated with

Also associated with

Rating

Process for producing nucleosides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for producing nucleosides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for producing nucleosides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-138182