Process for producing nucleic acid derivative

Details Process for producing nucleic acid derivative Process for producing nucleic acid derivative

2005-05-31

2005-05-31

Peselev, Elli (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S028100, C536S028700

Reexamination Certificate

active

06900298

ABSTRACT:
A process for efficiently producing a nucleic acid derivative by condensing a specific nitrogen-containing heterocyclic compound such as a dinitrogen 6-membered heterocyclic compound or a trinitrogen 5-membered heterocyclic compound with a pentose using a less expensive and safe reagent. Namely, a process for producing a nucleic acid derivative by condensing a dinitrogen 6-membered heterocyclic compound or a trinitrogen 5-membered heterocyclic compound with a pentose in the presence of an iron halide.

REFERENCES:
patent: 1216766 (1999-05-01), None
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H. Jin, et al., Tetrahedron: Asymmetry, vol. 4, No. 2, XP-001145857, pp. 211-214, “Unexpected Effects of Lewis Acids in the Synthesis of Optically Pure 2'-Deoxy-3'-Oxacytidine Nucleoside Analogues”, 1993.

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