Process for producing non-ionic radiographic contrast media util

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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560 16, 548462, C07C23365

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active

051911191

ABSTRACT:
Methods are provided for substituting aromatic carboxylic acids and derivatives thereof and amino substituted aromatic carboxylic acids and derivatives thereof, by forming imides and imide-amides, respectively, by acylation with aliphatic carboxylic acids, substituting at least one nitrogen atom under mild basic conditions with an aliphatic compound having as alkylating agent a displaceable functionality and removing undesired acyl groups, as appropriate.

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