Process for producing N-substituted polyhydroxy nitrogen-contain

Details Process for producing N-substituted polyhydroxy nitrogen-contain Process for producing N-substituted polyhydroxy nitrogen-contain

1994-12-08

1997-12-09

Lankford, Jr., Leon B.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 84, 435 99, 435100, 435128, 435170, C12P 1902, C12P 1926

Patent

active

056959699

ABSTRACT:
A process for producing N-substituted amino compounds, a process for oxidizing an N-substituted amino compound with a microbe, or cell fragment or cell free extract thereof, and a process for oxidizing an N-substituted amino compound with a microbe, or cell fragment or cell free extract thereof and reducing the oxidized N-substituted amino compound to N-substituted-polyhydroxy piperidines based on N-substituted mannosamines, allosamines and altrosamines, N-substituted polyhydroxy pyrrolidines, and N-substituted polyhydroxy azetidines. In addition, a one pot process for producing N-substituted-polyhydroxy piperidines based on N-substituted mannosamines, allosamines and altrosamines, N-substituted polyhydroxy pyrrolidines, and N-substituted polyhydroxy azetidines from the respective sugar is disclosed. A second embodiment comprises novel compositions of N-substituted-amino-6-deoxy-2-ketohexuloses based on mannose, allose and altrose, N-substituted-amino-5-deoxy-2-ketopentuloses and 4-(N-substituted)-amino-1,3-dihydroxy-2-butanones.

REFERENCES:
patent: 3956337 (1976-05-01), Niwa et al.
patent: 4246345 (1981-01-01), Kinast et al.
patent: 4266025 (1981-05-01), Kinast et al.
patent: 4405714 (1983-09-01), Kinast et al.
patent: 4611058 (1986-09-01), Koebernick
patent: 4806650 (1989-02-01), Schroder et al.
patent: 4940705 (1990-07-01), Boshagen et al.
CA 95(17):148646x--Kinast, G. and Schedel, M., "A four-stage synthesis of 1-deoxynojirimycin with a biotransformation as the central reaction step"., Agnew. Chem., 93(9), 799-800 (1981).
CA 111(21):195290k--Von der Osten, C.H. et al., "Use of a recombinaant bacterial fructose-1,6-diphosphate aldolase in aldol reactions: preparative synethesis of 1-deoxynojirimycin, 1-deoxynojirimycin, 1,4-dideoxy-1, 4-imino-D-arabinitol, and fagomine", J. Am. Chem. Soc.,111(11), 3924-7 (1989).
Kagan, et al., "The Preparation of Glycamines", J. Am. Chem. Soc., 79: 3541-44 (1957).
Mitts, E. and Hixon, R.M., "The Reaction of Glucose with Some Amines", J. Am Chem. Soc., 66:483-6 (1944).
Mohammed, A. and Olcott, H.S. "Relative Stabilities of D-Glucose-Amine Derivatives", J. Am. Chem. 66-969 (1947).
White, S.A. and Clause, G.W., "Effect of Intracytoplasmic Membrane Development on Oxidation of Sorbitol and Other Polyols by Gluconobacter oxydans", J. of Bacteriology, 150:934-43 (1982).
Rylander, Paul N, "Hydrogenation Methods", Academic Press, pp. 82-93 (1985).
Tiwari, et al., Carbohydrate Research 156, 19-24 (1986).

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