Process for producing N-acyl-L-methionine

Details Process for producing N-acyl-L-methionine Process for producing N-acyl-L-methionine

1975-03-03

1976-06-15

Monacell, A. Louis

Textiles: fiber preparation

195 2, C12B 100

Patent

active

039635732

ABSTRACT:
A process for producing optically pure N-acyl-L-methionine comprising (1) subjecting an N-acyl-D,L-methionine ester to the action of a proteolytic enzyme selected from the group consisting of sulfhydryl proteinases and microbially derived serine proteinases; and (2) separating the resulting N-acyl-L-methionine. The N-acyl group can be chemically removed to provide L-methionine.

REFERENCES:
patent: 2511867 (1950-06-01), Neuberg et al.
Brenner et al., "A Simple Enzymatic Method for the Preparation of D and L Methionine" Helv. Chim. Acta. 32 pp. 333-337 (1949).
Perlman et al., "Methods in Enzymology" vol. XIX Proteolytic Enzymes Academic Press 1970 pp. 226-244 and pp. 199-215.

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