Process for producing N-acetyl-D-glucosamine

Details Process for producing N-acetyl-D-glucosamine Process for producing N-acetyl-D-glucosamine

1996-02-20

1999-12-07

Saucier, Sandra E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435911, 435945, 435822, 435881, C12P 1926

Patent

active

059981733

ABSTRACT:
This invention pertains to a novel process for directly producing N-acetyl-D-glucosamine from chitin. More particularly, this invention pertains to a novel process for producing N-acetyl-D-glucosamine utilizing an ensemble of the chitinase family of enzymes to hydrolyze chitin of crustacea shells. The invention includes a process for producing N-acetyl-D-glucosamine by enzymatically hydrolyzing chitin with an ensemble of chitinolytic enzymes, including chitinase and chitobiase. In particular, using a two-stage chitin-hydrolysis reactor.

REFERENCES:
patent: 5061627 (1991-10-01), Olsen et al.
patent: 5262310 (1993-11-01), Karube et al.
Monreal et al., "The Chitinase of Serratia marcescens", Can. J. Microbiology, 1969, vol. 15, pp. 689-696.
Vyas et al., "Cnitinase production by Myrothecium verrucaria and its significance for fungal mycelia degradation", J. Gen. Appl. Microbiol. 1989, vol. 35, pp. 343-350.
Neugebauer et al., "Chitinolytic properties of Streptomyces lividans", Arch. Microbiol., 1991, vol. 156, pp. 192-197.
Cosio et al. "Bioconversion of shellfish chitin waste: waste pretreatment, enzyme production, process design and econoic analysis", Journal of Food Science, 1982, vol. 47, pp. 901-905.
Biotechnology. Edited by H.J. Rehm and G. Reed, VCH, 1985, vol. 2, "Fundamentals of Biochemical Engineering", pp. 302-309.
Biotechnology. Edited by H.J. Rehm and G. Reed, VCH, 1987, vol. 7a, "Enzyme technology", pp. 527-531.
Chemical Abstract No. 115:230433, 1991.

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