Process for producing liposome composition

Details Process for producing liposome composition Process for producing liposome composition

1988-08-15

1989-11-28

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Biocides; animal or insect repellents or attractants

424450, 264 41, 264 43, 264 46, 4284022, A61K 3722, A01N 2526

Patent

active

048836656

ABSTRACT:
Liposome composition is prepared by freezing liposomes in which a hydrophilic drug and one or more members selected from the group consisting of glucose, galactose, mannose, maltose and maltotriose are entrapped, in the presence of the aqueous solution of one or more members selected from the group of said saccharides. Thus obtained composition can be stably stored under freezing condition, and at thawing treatment, the leakage amount of the hydrophilic agent is exceedingly small.

REFERENCES:
patent: 4411894 (1983-10-01), Schrank et al.
Chemical Abstracts 102: 209232w (1984).
Chemical Abstracts 103: 200758K (1985).
Chemical Abstracts 102: 209232w (1984).

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