Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1973-12-07
1976-10-05
Rizzo, Nicholas S.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424246, C07D51514
Patent
active
039844013
ABSTRACT:
A 3-hydroxymethylcephalosporin which is not protected at the carboxyl group can be directly oxidized with a hexavalent chromium compound to give in good yield a lactol type cephalosporin represented by the general formula: ##SPC1##
Wherein R.sup.1 is hydrogen or an alkoxy group and R.sup.2 is an acylamino, or imido group. The resulting compounds are very useful and important as intermediates for preparing, e.g. 3-alkoxyiminomethyl cephalosporins.
REFERENCES:
patent: 3351596 (1967-11-01), Chamberlin
patent: 3682903 (1972-08-01), Bickel
Houben-Weyl, Methoden Der Organischen Chemie, Band VI/2, 1963, p. 716.
Imashiro Yoshio
Minamida Isao
Miyawaki Toshio
Numata Mitsuo
Shiraishi Mitsuru
Rizzo Nicholas S.
Takeda Chemical Industries Ltd.
Vaughn Mary C.
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