Process for producing L-tryptophan by fermentation

Details Process for producing L-tryptophan by fermentation Process for producing L-tryptophan by fermentation

1982-11-24

1985-12-24

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

4351721, 435839, C12P 1322, C12N 1500, C12R 1125

Patent

active

045606528

ABSTRACT:
A process for economically producing L-tryptophan which involves culturing aerobically in a culture medium a mutant of the genus Bacillus which is resistant to azaserine and a tryptophan analogue and recovering the L-tryptophan produced which accumulates in the culture medium.

REFERENCES:
patent: 3700558 (1972-10-01), Thiemann et al.
patent: 3700559 (1972-10-01), Shiio et al.
patent: 3801457 (1974-04-01), Arima et al.
patent: 3849251 (1974-11-01), Nakayama et al.
patent: 4363875 (1982-12-01), Akashiba et al.
Chemical Abstracts, vol. 92, No. 17, p. 279, Abstract No. 143110(w), Bazzicalupo, M. et al., "Characterization of 5-Fluoroindole and 5-Fluorotryptophan Resistant Mutants in Bacillus subtilis".
The Merck Index, 9th Edition, Windholtz, M. et al. ed., Merck and Co., Inc., Rahway, N.J., p. 240 (1976).
Metabolic Inhibitors, vol. I, Hochster, R. M. et al., ed., Academic Press, New York, pp. 53-57, 215-218 (1963).

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