Process for producing L-threonine

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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4352528, 4351721, 435849, C12P 1308, C12N 120, C12N 1500

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active

050174835

ABSTRACT:
A process is disclosed for producing L-threonine, the process involves culturing in a medium a microorganism of the genus Escherichia capable of producing L-threonine which has resistance to at least one of rifampicin, lysine, methionine, aspartic acid and homoserine, or a decreased ability to degrade L-threonine, accumulating L-threonine in the culture liquor and recovering L-threonine therefrom.

REFERENCES:
patent: 3494830 (1970-02-01), Nakayama et al.
patent: 3622453 (1971-11-01), Akeyama
Chemical Abstracts, vol. 95, No. 5, Aug. 1981, p. 580, abstract No. 40855a, Columbus, Ohio, U.S., & JP-A-81 10 037, Kyowa Hakko Kogyo Co., Ltd., 05-03-1981.
Research and Development in Japan, Awarded the Okochi Memorial Prize, 1984, pp. 43-49, Okochi Memorial Found., Tokyo, JP; M. Kismi et al., "Development of New Ferment. Method for Amino Acid Production by Intracellular . . . ".
Stanbury et al., Principles of Fermentation Technology, Pergamon Press, 1984.
Cohen, G., In Amino Acids: Biosynthesis and Genetic Regulation, 1983, pp. 147-158.
Lynn et al., In Amino Acids: Biosynthesis and Genetic Regulation, 1983, pp. 173-185.
Sikyta, B., Methods in Industrial Microbiology, 1983, pp. 238-239.

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