Process for producing L-lysine by fermentation with a bacteria h

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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4352521, 435840, 435843, C12P 1308, C12N 120

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active

053626362

ABSTRACT:
A process for producing L-lysine, which comprises culturing a mutant L-lysine-producing strain belonging to the genus Brevibacterium or the genus Corynebacterium and having selenalysine resistance in a nutrient medium, producing and accumulating L-lysine in the culture broth and collecting L-lysine from the culture broth.

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patent: 4066501 (1978-01-01), Tosaka et al.
Hirao, T. et al., "L-Lysine Production in Continuous Culture of An L-Lysine Hyperproducing Mutant of Corynebacterium glutamicum," Appl. Microbiol. and Biotechnology vol. 32, 1989, pp. 269-273.
Tosaka et al., "Lysine" In: Biotechnology and Amino Acid Production, Aida et al. (eds); vol. 24; Elsevier; 1986; pp. 152-172.
Chemical Abstracts, vol. 102, No. 1, Jan. 7, 1985, No. 59035T, E. Shimizu, et al., "Effect of a Selenium Analog of L-Lysine On Lysine Transport of Candida Pelliculosa".
Chemical Abstracts, vol. 101, No. 1, Jul. 2, 1984, No. 51438K, V. Busiello, et al., "Effects of Thialysine and Selenalysine On Lysine Biosynthesis".
Chemical Abstracts, vol. 103, No. 1, Jul. 8, 1985, No. 3377J, M. Di Girolamo, et al., "Effects of Selenalysine On Lysine Biosynthesis".

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