Process for producing L-histidine by fermentation

Details Process for producing L-histidine by fermentation Process for producing L-histidine by fermentation

1984-02-24

1988-02-16

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

435253, 435843, C12P 1324, C12N 120, C12R 115

Patent

active

047255412

ABSTRACT:
L-histidine is produced by culturing, in a nutrient medium, an L-histidine producing mutant microorganism belonging to the genus Corynebacterium. The mutant is resistant to a precursor for ubiquinone biosynthesis. L-histidine is accumulated in the culture liquor and is recovered therefrom.

REFERENCES:
patent: 3676301 (1972-07-01), Nakajima et al.
patent: 3713977 (1973-01-01), Nakayama et al.
patent: 4495283 (1985-01-01), Araki et al.
Frunzio et al, Proc. Natl. Acad. Sci., vol. 78(5), pp. 2767-2771, May 1981, "In Vivo and in Vitro Detection of the Leader RNA of the Histidine Operon of Escherichia coli K-12".
Bruni et al, J. Bacteriology, vol. 142(1), pp. 32-42, Apr. 1980, "Structure and Physiological Studies of the Escherichia coli, Histidine Operon Inserted into Plasmid Vectors".
Grisolia et al, J. Bact., vol. 142(1), pp. 692-700, Aug. 1982, "Cloning and Expression of the Distal Portion of the Histidine Operon of Escherichia coli K-12".

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