Process for producing L-histidine by fermentation

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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4351721, 435840, 435843, 435253, C12P 1324, C12N 1500, C12N 120, C12R 113, C12R 115

Patent

active

044952830

ABSTRACT:
L-histidine is produced by culturing, in a nutrient medium, an L-histidine producing mutant microorganism belonging to the genus Corynebacterium or Brevibacterium. The mutant is resistant to growth inhibition by an RNA polymerase inhibitor or requires adenine. L-histidine is accumulated in the culture liquor and is recovered therefrom.

REFERENCES:
patent: 3713977 (1973-01-01), Nakayama et al.
patent: 3816258 (1974-06-01), Arai et al.
patent: 3875001 (1975-04-01), Kubota et al.

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