Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Reexamination Certificate
2007-04-10
2007-04-10
Saidha, Tekchand (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
C435S183000, C435S193000, C435S252330, C435S320100, C536S023200
Reexamination Certificate
active
10239092
ABSTRACT:
According to the present invention, by using a microorganism having the ability to produce the L-amino acid which carries the avtA gene encoding alanine-valine transaminase (transaminase C) and whose alanine-valine transaminase activity is enhanced compared with its parent strain, it is possible to reduce the production of by-product amino acids which disturb purification in L-amino acid production by fermentation, and an industrially advantageous process for producing an L-amino acid can be provided.
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Wang, et al., “Cloning and Characterization of theEscherichia coliK-12 Alanine-Valine Transaminase (avtA) Gene”, Journal of Bacteriology vol. 169, No. 9 (1987), pp. 4228-4234.
Whalen, et al., “Analysis of an avtA::Mu d1 (AP lac) Mutant: Metabolic Role of Transaminase C”, Journal of Bacteriology, vol. 150, No. 2 (1982), pp. 739-746.
Abe Yayoi
Ikeda Masato
Takano Jun-ichi
Yagasaki Makoto
Fitzpatrick ,Cella, Harper & Scinto
Fronda Christian L.
Kyowa Hakko Kogyo Co. Ltd.
Saidha Tekchand
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