Process for producing interferon

Details Process for producing interferon Process for producing interferon

1981-05-20

1984-02-21

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

435 70, 435240, 435811, C12P 2100, C12P 2102, C12N 500

Patent

active

044330529

ABSTRACT:
In producing interferon by treating animal cells proliferated on a microcarrier with an interferon inducer, the cells on the microcarrier are treated with a negatively charged water-soluble macromolecular material.

REFERENCES:
patent: 3773924 (1973-11-01), Ho et al.
patent: 4007086 (1977-02-01), Hamilton
patent: 4036693 (1977-07-01), Levine et al.
patent: 4189534 (1980-02-01), Levine et al.
patent: 4266024 (1981-05-01), Swetly et al.
Dianzani et al; Chem. Abstr. 69:65797j (1968).
Vilcek et al; Chem. Abstr. 78:66844v (1973).
Borden et al; Antimicrobial Agents and Chemotherapy 13, 159 (1978).
Stenesh: Dictionary of Biochemistry, J. Wiley & Sons, New York, 1975, p. 188.
Glucocorticoid Hormones Inhibit DNA Synthesis and Enhance Interferon Production in Human Lymphoid Cells Lines, G. R. Adolf and P. Swetly, Nature 282: 736-738 (Dec. 13, 1979).
Growth of Cell Strains on Micro-Carriers in Homogeneous Culture, A. L. vanWezel, Nature 216: 64-65 (Oct. 7, 1967).

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