Process for producing indoles

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D20908

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active

047571527

ABSTRACT:
A process for producing an indole by catalytic reaction of a 2-(o-aminoaryl)ethanol, said reaction being carried out by heating in a liquid phase in the presence of an alkali metal using a catalyst containing a metal selected from the group consisting of a platinum-group metal, nickel and copper.
The process is industrially advantageous in that indoles are produced in high yield.

REFERENCES:
patent: 3699120 (1972-10-01), Bakke et al.
patent: 3984434 (1976-10-01), O'Murchu 548508
Acta. Chim. Acad. Sci. Hung., 54, 167 (1967).
Derwent Abstract of Japanese Laid-Open Appl. No. 142063, May 19, 1976.
Roczniki, Chem., 38, 507 (1964).
J. Org. Chem., 29, 1540 (1964).
Derwent Abstract of Japanese Patent Publication No. J85007619 (Feb. 1985), Mitsui Petrochem.

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