Process for producing hyaluronic acid or its derivative

Details Process for producing hyaluronic acid or its derivative Process for producing hyaluronic acid or its derivative

2006-09-12

2006-09-12

Prats, Francisco (Department: 1651)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

C435S072000, C536S123000, C536S123100, C536S126000

Reexamination Certificate

active

07105320

ABSTRACT:
It is to provide a method for producing hyaluronic acid or a hyaluronic acid derivative which is a simple preparation method as compared with a cockscomb extraction method or a fermentation method which has conventionally been employed industrially, and with which isolation and purification of the product from the reaction liquid is easy. It is a method for producing hyaluronic acid or a hyaluronic acid derivative, which comprises acting a hyaluronidase on an oxazoline derivative.

REFERENCES:
patent: 9-3088 (1997-01-01), None
S. Kobayashi et al.: “Enzymatic polymerization to artificial hyaluronan: A novel method to synthesize a glycosaminoglycan using a transition state analogue monomer” J. Am. Chem. Soc., vol. 123, No. 47, pp. 11825-11826 Nov. 28, 2001.
Shiro Kobayashi et al.: “GlcA-beta (1-3)-GlcNAc oxazoline yudotai o shinki kishitsu monomer to shita koso shokubai jugo ni yoru hyaluronic acid no gosei” Chemical Society of Japan Koen Yokoshu, vol. 79, No. 2, p. 815 Mar. 15, 2001.
Shiro Kobayashi et al.: “Hiarobiuroneto oxazoline yudotai o sen'i jotai analogue kisitsu to shita koso shokubai jugo ni yoru jinko hyaluronic acid no gosei” Polymer Preprints, Japan, vol. 50, No. 14, p. 3517 Aug. 28, 2001.
Shiro Kobayashi et al.: “Koso shokubai jugo ni yoru jinko hyaluronic acid no gosei” Polymer Preprints, Japan, vol. 50, No. 5, p. 997 May 7, 2002.
Shiro Kobayashi et al.: “Hyaluronidase koso shokubai jugo ni yoru jinko hyaluronic acid no gosei” Nihon Toshitsu Gakkai Nenkai Yoshishu, p. 146 Jul. 2, 2001.
S. Kobayashi et al.: “Enzymatic ring-opening polyaddition for chitin synthesis: a cationic mechanism in basic solution?” Macromol. Symp., vol. 132, pp. 415-420 1998.
S. Kobayashi et al.: “Synthesis of artificial chitin: irreversible catalytic behavior of a glycosyl hydrolase through a transition state analogue substrate” J. Am. Chem. Soc., vol. 118, pp. 13113-13114 1996.
D.L. Claudio et al.: “Enzymatic synthesis of hyaluronic acid with regeneration of sugar nucleotides” J. Am. Chem. Soc., vol. 117, pp. 5869-5870 1995.
S. Kobayashi et al.: “Novel method for polysaccharide synthesis using an enzyme: the first in vitro synthesis of cellulose via a nonbiosynthetic path utilizing cellulose as catalyst” J. Am. Chem. Soc., vol. 113, pp. 3079-3084 1991.
R.W. Jeanloz et al.: The synthesis of P-[2-acetamido=2-deoxy-3-0(Beta-D-glucopyranosyluronic acid)-alpha-D-glucopyranosyl]P-dolichyl diphosphate (N-acetyl hyalobio syluronic dolichyl diphosphate) Carbohydrate Research, vol. 68, pp. 343-363 1979.
Hiromi Saitoh et al.: “Enzymic reconstruction of glycosaminoglycan oligosaccharide chains using the transglycosylation reaction of ovine testicular hyaluronidase” The Journal of Biological Chemistry, vol. 270, No. 8, pp. 3741-3747 1995.

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