Process for producing human serum albumin

Details Process for producing human serum albumin Process for producing human serum albumin

1994-11-28

1997-05-20

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using a micro-organism to make a protein or polypeptide

435 691, 435171, 435911, 435942, C12P 2100, C12P 2102, C12N 114

Patent

active

056311451

ABSTRACT:
A process for producing recombinant human serum albumin (HSA) which comprises culturing an HSA producing host prepared by gene manipulation techniques at a temperature of from 21.degree. to 29.degree. C. Culturing the HSA producing host under such a specified temperature condition makes it possible to increase productivity of HSA production, improve the growth yield of an HSA producing host, and reduce the degree of coloring in the HSA preparation.

REFERENCES:
patent: 4746608 (1988-05-01), Mizukami et al.
patent: 5330901 (1994-07-01), Prevatt et al.
patent: 5334512 (1994-08-01), Kobayashi et al.
patent: 5369020 (1994-11-01), Sumi et al.
Derwent Abs. WPIL 94:146982/18 Tonen Corp (JP 06090742) Apr. 5, 1994.
Derwent Abs WPIL 94-226852/28 Green Cross Corp (EP-606917) Jul. 20, 1994.
Derwent Abs WPIL 90-093372/13 Fleer et al (FR 2635113) Feb. 9, 1990.
APS Abs (Japan 06-100892) Washimi et al Jul. 13, 1994.

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