Process for producing human lysozyme

Details Process for producing human lysozyme Process for producing human lysozyme

1977-07-13

1978-08-01

Marantz, Sidney

Textiles: fiber preparation

260112B, C07G 7026

Patent

active

041041259

ABSTRACT:
It has been discovered that lysozyme in the blood is concentrated into the albumin fraction when the blood is fractionated by the alcohol fractionation method at lowered temperature or the ammonium sulfate fractionation method. Lysozyme can be produced by contacting the albumin fraction with a weakly acidic cation-exchanger such as CM-cellulose to adsorb selectively the lysozyme with the cation-exchanger and then eluting the lysozyme adsorbed from the cation-exchanger.

REFERENCES:
patent: 2705230 (1955-03-01), Reid
patent: 2765299 (1956-10-01), Porsche
patent: 2958628 (1960-11-01), Hink, Jr.
patent: 3850903 (1974-11-01), Garcia
patent: 3859435 (1975-01-01), Bruzzese
patent: 3926939 (1975-12-01), Ivanov
patent: 3940317 (1976-02-01), Katz
patent: 4017470 (1977-04-01), Izaka
Chemical Abstracts, 70: 9066d (1969).
Chemical Abstracts, 73: 36084b (1970).
Chemical Abstracts, 77: 86595x (1972).
Chemical Abstracts, 82: 166992 (1975).
Chemical Abstracts, 83: 143697g (1975).
Science, 155, 1536-1537, (Mar. 24, 1967).

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