Process for producing glycoside

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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Reexamination Certificate

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07622563

ABSTRACT:
A glycoside in which at least two phenolic hydroxyl groups of a compound having at least two phenolic hydroxyl groups in its molecule are glycosidically linked to anomeric carbon atoms of at least two sugar molecules can be prepared with high yield by a method including the step of allowing phenolic hydroxyl groups of a compound having at least two phenolic hydroxyl groups in its molecule to react with sugar molecules each having an acetylated hydroxyl group attached to an anomeric carbon atom in the presence of an organic solvent and an acid catalyst while removing acetic acid formed during the reaction from the reaction system.

REFERENCES:
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patent: 2002-193990 (2002-07-01), None
March et al, General Organic & Biochemistry, 5th Ed., 1998, p. 464.
Elly Smits et al., “Reliable method for the synthesis of aryl β-D-glucopyranosides, using boron trifluoride-diethyl ether as catalyst” Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry, 1996, pp. 2873-2877, Coden: JCPRB4, ISSN: 0300-922X.
Smits et al., “Reliable method for the synthesis of aryl β-D-glucopyranosides, using boron trifluoride-diethel ether as catalyst,”J. Chem. Soc., 1996, vol. 24, pp. 2873-2877.

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