Process for producing glycidyl ether

Details Process for producing glycidyl ether Process for producing glycidyl ether

2007-09-04

2007-09-04

Dentz, Bernard (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

10515384

ABSTRACT:
A process for producing a glycidyl ether and an optically active compound thereof with high yield and an optically high purity comprising reacting an alcohol with epihalohydrin in a base to thereby produce a glycidyl ether, the reaction performed in a two-layer system of a nonaqueous organic solvent and an aqueous solvent.

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P. Camps et al.,“Stereoselective Syntheses of both Enantiomers of Ketoconazole from (R)- and (S)-Epichlorohydrin”, Tetrahedron Asymmetry, vol. 6, No. 6, pp. 1283-1294, Jun. 1995.
V. Brizzi et al., “New 1,2,4-Oxadiazole Derivatives: Synthesis and Adrenergic Receptors Binding Studies”, IL FARMACO, vol. 47, No. 6, pp. 953-966, Jun. 1992.

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