Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1995-05-23
1998-08-04
Lankford, Jr., Leon B.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
435134, 435146, 435126, C12P 762, C12P 764
Patent
active
057892121
ABSTRACT:
The invention provides a process for producing gamma-lactones useful for incorporation in flavorings and fragrances, wherein a micro-organism which is acceptable for making food grade products and which does not metabolize gamma-lactones, is cultured aerobically in a culture medium containing as the substrate a hydroxy fatty acid having an even number 4 of carbon atoms between the carboxyl group and the carbon atom carrying the hydroxy group. The preferred micro-organism is a Saccharomyces cerevisiae, Debaromyces hansenii or Candida boidinii species. The gamma-hydroxy-alkanoic acid reaction product of the process is lactonized either in the fermentation broth or after separation therefrom. Especially suitable are 12-hydroxy fatty acids such as ricinoleic acid. The hydroxy fatty acid may be added either pure or as the mixture obtained by hydrolysis of an ester thereof. Enzymatic hydrolysis of such ester may be done in situ in the fermentation broth.
REFERENCES:
patent: 3076750 (1963-02-01), Muys et al.
patent: 4560656 (1985-12-01), Farbood et al.
Patent Abstracts of Japan, vol. 9, No. 241, Sep. 27, 1985; and No. 196, Aug. 13, 1985.
Okuyame et al., Production of Castor Oil Having Improved Quality.
Okuyama et al., Cosmetics.
Boog Arnoldus L. G. M.
Peters Alfons L. J.
Roos Robert
Van Grinsven Adrianus M.
Wieg Andras J.
Lankford , Jr. Leon B.
Unilever Patent Holdings B.V.
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