Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Patent
1994-09-14
1997-01-14
Marx, Irene
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
435118, 435117, 435125, 435127, 435886, C12P 1718
Patent
active
055938701
ABSTRACT:
The present invention is directed to a process for producing frenolicin B. The process comprises fermenting a broth so as to produce frenolicin, said broth having a microorganism capable of producing frenolicin. The frenolicin is then converted in the broth under anaerobic conditions to deoxyfrenolicin. The deoxyfrenolicin is converted to frenolicin B.
REFERENCES:
patent: 4199514 (1980-04-01), Omura et al.
Staubury et al., "Principles of Fermentation Technology", 1984, pp. 33-47.
Van Meter et al., Antimicrobial Agents Annual 1960, pp. 77-80, Gray et al., eds.. Plenum Press, New York 1961.
Iwai et al., J. of Antibiotics 31:959-965.
Belter et al., Bioseparations--Downstream Processing for Biotechnology, Wiley-Interscience Publications, pp. 17, 25, 99, 105, 109 (1988).
Block David E.
Hermann Theron E.
Hsieh Jih-Han
Mehta Nikhil S.
Rai Vishva R.
Hoffmann-La Roche Inc.
Johnston George W.
Marx Irene
Silverman Robert A.
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