Process for producing fat emulsion

Details Process for producing fat emulsion Process for producing fat emulsion

1995-04-07

1996-07-09

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514356, 514359, 514404, 514538, 514558, 514762, 514937, 514943, A61K 3120, A61K 3144, A61K 4730, A61K 4744

Patent

active

055345026

ABSTRACT:
Stable homogeneous fatty emulsions containing amphotericin B are prepared. According to one embodiment, amphotericin B is decrystallized using an acid and ethanol and then homogeneously dispersed in a lipid, following which it is emulsified.
According to a second embodiment, amphotericin B crystals are kneaded until their presence can no longer be confirmed and the decrystallized amphotericin B is thereafter uniformly dispersed in a lipid and, thereafter, emulsified.

REFERENCES:
patent: 4711902 (1987-12-01), Serno
patent: 4784845 (1988-11-01), Desai et al.
patent: 5229422 (1993-07-01), Takahashi et al.
patent: 5236955 (1993-08-01), Gordon
patent: 5244925 (1993-09-01), Wretlind et al.

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