Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-10-17
2010-12-28
Morris, Patricia L (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
07858801
ABSTRACT:
The present invention relates to a process for preparation of optically pure (S)-amlodipine-L-hemitartrate DMF solvate comprising the steps of treating (R,S) amlodipine base with L-tartaric acid in the presence of dimethyl formamide and a co-solvent. The invention also relates to a process for converting (R) or (S)-amlopidine-L-hemitartrate DMF solvate into their besylates without isolating free chiral amlopidine base after solution.
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Bhawal Baburao Manikrao
Deshmukh Rajendra Dagadu
Gharpure Milind Moreshwar
Mehta Satish Ramanlal
Ranade Prasad Vasudeo
Emcure Pharmaceuticals Limited
Foley & Lardner LLP
Morris Patricia L
LandOfFree
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