Process for producing easily absorbable amorphous steryl glucosi

Details Process for producing easily absorbable amorphous steryl glucosi Process for producing easily absorbable amorphous steryl glucosi

1976-05-05

1978-12-12

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugate includes potentiator; or composition comprising...

536 5, A61K 31705, C07G 300

Patent

active

041296494

ABSTRACT:
A process for producing amorphous preparations of steryl glucoside monopalmitates, wherein steryl glucoside monopalmitates are heated at a temperature above 110.degree. C up to about 145.degree. C or the compounds are dissolved in an organic solvent in which they are soluble with a solvent which is then distilled off, and the compounds then pulverized and mixed with physiologically harmless organic or inorganic fine particles in a proportion of 0.5 times (by weight) of the compounds or more, thereby homogeneously dispersing the amorphous compounds in the fine particles or uniformtly adsorbing the compounds on the fine particles, and the resulting preparations which have hemostatic properties and are readily absorbable upon ingestion. The starting steryl glucoside monopalmitates are obtained in crystalline form as from soy beans or other vegetable sources.

REFERENCES:
patent: 2746957 (1956-05-01), Perlman et al.
patent: 3036060 (1962-05-01), Lucas et al.
patent: 3238104 (1966-03-01), Madaus et al.
patent: 3753975 (1973-08-01), Kaiser
Kirk-Ohmer, "Encylop. of chemical Technology", Crystalization, pp. 492-493, vol. 6, 2nd Ed., 1965, Wiley & Sons, Inc.
Kisilev et al., "On Phase Transformations of Dextran", Chem. Abst., vol. 84, 1976, p. 137553M.
Kirk-Othmer, "Encyclopedia of Chem Tech.", vol. 13, pp. 212-213.

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