Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Patent
1991-06-04
1992-07-14
Robinson, Douglas W.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
4352521, 435227, 435228, 435280, C12P 1306, C12N 978, C12N 120
Patent
active
051302403
ABSTRACT:
A novel D-amidase is described. The enzyme specifically hydrolyzes D-.alpha.-alanineamide into D-.alpha.-alanine. It is produced by culturing a microorganism belonging to the genus Arthrobacter, and is useful as an enzyme for efficiently producing D-.alpha.-alanine having a high optical purity and/or L-.alpha.-alanineamide from DL-.alpha.-alanineamide or D-.alpha.-alanineamide at low cost.
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Asano, Y., et al. 1988, "Enzymatic Synthesis of D-amino acid amides (I)," Nippon Nogei Kagaku Kaisha, vol. 62 (3) p. 352. (English translation).
Foster, D. L., and Fillingame, R. H. 1979. "Energy-transducing ATPase of Escherichia coli". Journal of Biological Chemistry, vol. 254 (17) pp. 8230-8236.
Goodfellow, M., and Cross, T. "Classification". In The Biology of the Actinomycetes, Ed. Goodfellow, M., et al. 1984 Academic Press, London. pp. 40-44.
Patent Abstracts of Japan, vol. 11, No. 13 (2460).
Hashimoto Yukio
Kawamoto Isao
Kawasaki Hideki
Ochiai Keiko
Ozaki Akio
Knode Marian C.
Kyowa Hakko Kogyo Co. Ltd.
Robinson Douglas W.
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