Process for producing cytotoxic T-cells and compositions produce

Details Process for producing cytotoxic T-cells and compositions produce Process for producing cytotoxic T-cells and compositions produce

1987-09-08

1989-06-13

Moskowitz, Margaret

Chemistry: molecular biology and microbiology

Spore forming or isolating process

430 1, 430 2, 4302402, C12N 500

Patent

active

048392901

ABSTRACT:
A method of inducing antitumor immunocytes which is simple in operation and suitable for inducing antitumor immunocytes having not only excellent cytotoxic activity against tumor cells but also high safety, which method comprises contacting leucocytes with an insoluble, antitumor immunocyte-inducing material capable of linking with T cells, said antitumor immunocyte-inducing material comprising an insoluble carrier and a ligand linked therewith. The induced antitumor immunocytes can be simply separated in substantially ligand-free form from the insoluble, antitumor immunocyte-inducing material. The obtained antitumor immunocytes have not only excellent cytotoxic activity against tumor cells but also high safety.

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