Process for producing chroman compound

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C549S407000, C549S408000

Reexamination Certificate

active

07615650

ABSTRACT:
The invention provides a process for producing a chroman compound represented by formula (1), characterized in that the process includes allowing a phenol, an unsaturated compound, and a formaldehyde to react in the absence of catalyst and in the presence of water in an amount by mole 1 to 10 times that of the phenol.According to the present invention, a high-purity chroman compound can be produced in the absence of catalyst and under mild conditions. In addition, the invention provides an industrial means for producing the compound, without using a large amount of an acid or a base serving as a reaction promoter or a catalyst, which would otherwise cause side reactions, apparatus corrosion, etc.

REFERENCES:
patent: 0 645 383 (1995-03-01), None
patent: 0 891 974 (1999-01-01), None
patent: 60-092283 (1985-05-01), None
patent: 2003-146981 (2003-05-01), None
patent: WO 01/92249 (2001-12-01), None
Giancarlo Cravotto, et al., The Reactivity of 4-Hydroxycoumarin under Heterogeneous High-Intensity Sonochemical Conditions, Synthesis 2003, No. 8, pp. 1286-1291.
Supplementary European Search Report dated Feb. 16, 2009, for Application No. EP 05 70 4261.

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