Process for producing cephalosporanic acid derivatives

Details Process for producing cephalosporanic acid derivatives Process for producing cephalosporanic acid derivatives

1973-11-14

1976-12-21

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424246, 2602391, 2603067E, C07D50110

Patent

active

039988171

ABSTRACT:
Novel penicillin derivatives of the formula (I) ##STR1## wherein R.sup.1 represents a lower alkyl group and R.sup.2 represents an ester protective group, as hereinafter defined and 7-amino-3-desacetoxycephalosporanic acid derivatives of the formula (II) ##STR2## wherein R.sup.1 represents a lower alkyl group and R.sup.2 represents an ester protective group, which are useful as precursors for the production of cephalosporin derivatives, and an improved process for producing cephalosporin derivatives of the formula (II) above and the formula (III) ##STR3## wherein R.sup.2 is an ester protective group, are disclosed.

REFERENCES:
patent: 3275626 (1966-09-01), Morin et al.
patent: 3632850 (1972-01-01), Garbrecht
patent: 3725397 (1973-04-01), Graham et al.
patent: 3725399 (1973-04-01), Ellerton et al.
patent: 3852281 (1974-12-01), Verweij
patent: 3852295 (1974-12-01), Graham et al.
patent: 3862181 (1975-01-01), Davis et al.

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