Process for producing carboxylic acid amides

Details Process for producing carboxylic acid amides Process for producing carboxylic acid amides

1990-05-29

1992-08-25

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546170, 546313, 546317, 546318, 546319, 546321, 546193, 546281, 564184, 549 70, 540484, 548517, C07D21516, C07D21356, C07D33336, C07D23322

Patent

active

051420570

ABSTRACT:
A process for producing a carboxylic acid amide or ester, which comprises reacting an organic chloride having at least one chlorine atom on its ring of a substituted or unsubstituted, aromatic or heterocyclic hydrocarbon with carbon monoxide and an amine or an alcohol in the presence of a base by using as catalysts a palladium compound and a phosphine compound represented by the general formula (V):

REFERENCES:
patent: 3988358 (1976-10-01), Heck
patent: 4128554 (1978-12-01), Heck
J. Org. Chem. 1981, 46, pp. 4614-4617.

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