Process for producing carbamazepine

Details Process for producing carbamazepine Process for producing carbamazepine

2006-03-21

2006-03-21

McKenzie, Thomas C. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

Reexamination Certificate

active

07015322

ABSTRACT:
The invention concerns a process for producing 5H-dibenz[b,f]azepine-5-carboxamide (carbamazepine) by reacting iminostilbene with an alkali cyanate in acetic acid or a mixture of acetic acid with water or with alcohol.

REFERENCES:
patent: 277095 (1988-03-01), None
BPAI Decision in Appeal # 95-4841.
Austin Patterson, “A German-English Dictionary for Chemists”, 3rd Ed., Wiley, New York.
“Handbook of Chemistry and Physics, 42nd Edition”, Charles D. Hodgman Editor, The Chemical Rubber Publishing Co., Cleveland, OH, 1962, p 1753-1754.
Gmelins Handbuch der anorganischen Chemie, Kohlenstoff, Teil D 1, Dieter Koschel, Editor, Verlag Chemie, Weinheim, 1971, p 344.
Lowry and Richardson, Mechanism and Theory in Organic Chemistry, 3rd Edition, Harper and Row, New York, 1987, p 199.
Ruff, F. and Csizmadia, I.G. “Organic Reactions, Equilibria, Kinetics, and Mechanism”, Elsevier, New York, 1994, p. 60.
“Statement (Report) of Inspection/Quality Control”, Koytcheff, John M., Jul. 14, 2000.
Acklin (EP 277,095) translation, “Statement (Report) of Inspection/Quality Control”, Koytcheff, John M., Jul. 14, 2000.

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