Process for producing benzofuran derivative

Details Process for producing benzofuran derivative Process for producing benzofuran derivative

2006-04-25

2006-04-25

Dentz, Bernard (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C568S331000, C568S648000, C548S454000, C549S336000

Reexamination Certificate

active

07034166

ABSTRACT:
A novel process for efficiently and easily producing a compound represented by the formula:wherein ring A is a benzene ring that may be optionally further substituted in addition to the group represented by W, or a salt thereof; which comprises reacting a compound represented by the formula:wherein R1and R2are the same or different and each is a hydrogen atom, an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, Y is a halogen atom, ring A is a benzene ring that may be optionally further substituted in addition to the group represented by Y and ring B is an optionally substituted benzene ring, or a salt thereof, with a compound represented by the formula:in-line-formulae description="In-line Formulae" end="lead"?WHin-line-formulae description="In-line Formulae" end="tail"?wherein W iswherein ring C is an optionally substituted benzene ring, ring D is an optionally substituted 5- to 7-membered nitrogen-containing heterocyclic ring, R3is a hydrogen atom, an aliphatic hydrocarbon group containing an aromatic group or an acyl group, and R4is a hydrogen atom, an optionally substituted hydrocarbon group or an acyl group, or a salt thereof and thereafter, if necessary, deprotecting the resultant product, which is suitable for industrial production.

REFERENCES:
patent: 0483772 (1992-05-01), None
patent: WO 00/02887 (2000-01-01), None
patent: WO 02/28850 (2002-04-01), None
Kosugi, et al. “Palladium-Catalyzed Aromatic Amination of Aryl Bromides with N,N-DI-Ethylamino-Tributyltin” Chemistry Letters pp. 927-928 (1983).

Affiliated with

Also associated with

Rating

Process for producing benzofuran derivative does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for producing benzofuran derivative, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for producing benzofuran derivative will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3540372