Process for producing atenolol of high optical purity

Details Process for producing atenolol of high optical purity Process for producing atenolol of high optical purity

2006-01-03

2006-01-03

Kumar, Shailendra (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C549S514000, C549S515000, C549S516000

Reexamination Certificate

active

06982349

ABSTRACT:
The present invention relates to an improved process for producing optically active (S)-atenolol of formula (1) in high optical purity by reacting a phenol with an epichlorohydrin.

REFERENCES:
patent: 4085136 (1978-04-01), Tucker
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patent: 01-102072 (1989-04-01), None
patent: 3077856 (1991-03-01), None
patent: 04-198175 (1992-07-01), None
Kitaori, Kazuhiro, (1997) Chem. Pharm. Bull 45(2) 412-414.
Wilson, Michael, (1988) J. Chromatography (431) pp. 222-227.

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