Process for producing aromatic aldehyde

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

Reexamination Certificate

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C568S437000

Reexamination Certificate

active

07342138

ABSTRACT:
A process for producing an aromatic aldehyde compound represented by a general formula (3):(wherein R′ and n are as defined below), which comprises reacting a benzyl compound represented by a general formula (1):(wherein R may represents hydrogen atom, n represents an integer of 1 to 6, and R′ may be the same or different and represent a hydrogen atom or an alkyl gorup, an alkyl group or a phenyl group which may have a substituent) with an oxy-compound of bromine represented by the formula (2):in-line-formulae description="In-line Formulae" end="lead"?MBrOm  (2)in-line-formulae description="In-line Formulae" end="tail"?(wherein M represents a hydrogen atom or a metal atom, and m represents an integer of 1 to 3) in the presence of an acid catalyst. According to this method, an aromatic aldehyde compound can be produced in high selectivity by a simple operation without using an expensive catalyst or transition metal.

REFERENCES:
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patent: 09-087227 (1997-03-01), None
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Ahmad Shaabani et al., “NaBrO3-FeCl3as a new reagent for oxidation of benzylic and secondary alcohols to carbonyl compounds”, Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, vol. 40B (2), pp. 148-151, XP008066042.
Ahmad Shaabani et al., “Oxidation Deprotection of Trimethylsilyl Ethers to Carbonyl Compounds by NaBrO3-NH4Cl Reagent in Aqueous Acetonitrile”, Synthetic Communications, vol. 31, No. 5, pp. 759-765, 2001.

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