Process for producing aphidicolin using the microrganism vertici

Details Process for producing aphidicolin using the microrganism vertici Process for producing aphidicolin using the microrganism vertici

1991-07-18

1993-04-13

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435171, 435254, 435911, C12P 702

Patent

active

052022447

ABSTRACT:
Aphidicolin is produced with a high productivity by culturing microorganisms belonging to the genus Verticillium, for example, Verticillium sp FERM BP-3430, in a culture medium, thereby forming and accumulating aphidicolin therein and recovering the aphidicolin therefrom.

REFERENCES:
Starratt et al., "The Production of Aphidicolin by Nigrospora sphaerica", Can. J. Microbiol., vol. 20, pp. 416-417, 1974.
Fisher, P. J. et al., "Onychophora Coprophila-A New Fungus Producing Aphidicolin", Trans. Br. Mycol. Soc., vol. 83, No. 1, pp. 149-150, 1984.
Kawada, K. et al., "Isolation of Aphidicolin as an Root Growth Inhibitor from Harziella entomophilla", Agric. Biol. Chem., vol. 48, No. 8, pp. 1611-1612 1978.
Clayton, N. et al., "Insecticidal Secondary Metabolic Products From the Entomagenous Fungus Verticillium lecanii", J. Invertebr. Pathol., vol. 40, No. 3, pp. 413-418, 1982.

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