Process for producing antitumor antibiotic compound

Details Process for producing antitumor antibiotic compound Process for producing antitumor antibiotic compound

1985-09-25

1986-07-08

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using a micro-organism to make a protein or polypeptide

435253, 435822, C12P 2104, C12N 120, C12R 101

Patent

active

045993106

ABSTRACT:
A new cyclic depsipeptide antitumor antibiotic designated herein as sandramycin is produced by fermentation of a new microorganism, Nocardioides sp. strain C49,009, ATCC 39419. Sandramycin possesses antibacterial activity and inhibits the growth of tumors in experimental animals.

REFERENCES:
patent: 4360458 (1982-11-01), Koshiyama et al.
patent: 4451456 (1984-05-01), Koshiyama
The Journal of Antibiotics (1980) pp. 1087-1102.

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