Process for producing antibiotic A80438

Details Process for producing antibiotic A80438 Process for producing antibiotic A80438

1985-05-28

1989-05-16

Warren, Charles F.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435118, 435123, 435886, 435126, C12R 1465, C12P 1716, C12P 1702

Patent

active

048309672

ABSTRACT:
A new strain of Streptomyces pactum, NRRL 15970, and an improved fermentation process for producing the polyether antibiotic A80438 using this microorganism are provided.

REFERENCES:
patent: 3183154 (1965-05-01), Argoudelis et al.
patent: 3950514 (1976-04-01), Sawada
patent: 4591559 (1986-05-01), Liu et al.
T. Mizutani et al., "Lonomycins B and C: Two New Components of Polyether Antibiotics: Fermentation Isolation and Characterization," J. Antibiotics 33, 1224-1230 (1980).
J. W. Westley: "Polyether Antibiotics," vol. 1, pp. 1-11, 12 Chapter 1, Marcel Dekker Inc., New York.
Taylor et al., ibid., pp. 103 and 109-110.
S. Omura et al., "Isolation of a New Polyether Antibiotic, Lonomycin," J. Antibiotics 29 (1), 15-20 (1976).
C. Riche et al., "Crystal and Molecular Structure of Emericid: A New Polyether Antibiotic," J. C. S. Chem. Comm. 1975, 951-952.
M. Ohshima et al., "Antibiotic DE-3936, a Polyether Antibiotic Identical with Lonomycin; Taxonomy, Fermentation, Isolation and Characterization," J. Antibiotics 29 (4), 354-365 (1976).
N. Tsuji et al., "Two New Antibiotics, A-218 and K-41; Isolation and Characterization," J. Antibiotics 29 (1) 10-14 (1976).

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