Process for producing and obtaining anaphylatoxin- and cocytotax

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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435 68, 435 69, C07K 320, C07K 328

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active

046108157

ABSTRACT:
The invention relates to a process for producing and obtaining anaphylatoxin- and cocytotaxin-containing leucotaxine preparations and anaphylatoxin and cocytotaxin proteins in molecularly homogeneous, biologically active form from contact-activated mammalian serum by the following steps:

REFERENCES:
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Tack, B. F. et al., Biochemistry, vol. 15, No. 20, pp. 4513-4521, 1976.
Wissler, J., Eur J. Immunol. vol. 2, pp. 73-96, 1972.
Vallota, E., J. Exp. Med. vol. 137, pp. 1109-1123, 1973.
Gerard, C., J. Biol. Chem. vol. 254, pp. 6346-6351, 1979.
Conroy, M., J. Immunol. vol. 116, pp. 1682-1687, 1976.

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