Process for producing an intermediate of a new quinolone compoun

Details Process for producing an intermediate of a new quinolone compoun Process for producing an intermediate of a new quinolone compoun

1996-06-20

1997-04-22

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20902, C07D20952

Patent

active

056230788

ABSTRACT:
A production process with good efficiency, and applicable to production of a synthetic intermediate of a new quinolone anti-fungus agent CP-99219, is provided.
A production process of an intermediate of a new quinolone compound expressed by the formula (IV) ##STR1## wherein R.sup.3 represents a benzyl group, a diphenylmethyl group, etc. and R.sup.4 represents a linear or branched alkyl group of 1 to 8C, a cycloalkyl group, etc.
which process employs as a starting substance, a cyclopropanetricarboxylic acid triester expressed by the formula (I) ##STR2## wherein R.sup.1 and R.sup.2 represent a linear or branched alkyl group, a cycloalkyl group, an aryl group or an aralkyl group,
and passes through seven steps.

REFERENCES:
patent: 5256791 (1993-10-01), Braish

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