Process for producing amide compound

Details Process for producing amide compound Process for producing amide compound

1998-10-22

2000-03-28

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing nitrogen-containing organic compound

435227, 435232, 435800, 435803, C12P 1302, C12N 978, C12N 988

Patent

active

060430613

ABSTRACT:
A process for producing an amide compound is described, wherein from a nitrile compound, the corresponding amide compound is produced by the action of nitrile hydratase, characterized in that the hydrocyanic acid concentration in a composition containing the nitrile compound is reduced by a chemical process, and thereafter nitrile hydratase acts on the nitrile compound. According to the invention, the decrease of the activity of the enzyme nitrile hydratase can be effectively suppressed so that an amide compound can be effectively produced from a nitrile compound.

REFERENCES:
patent: 2481580 (1949-09-01), Dreyfus
patent: 5519162 (1996-05-01), Agarwal et al.
patent: 5866379 (1999-02-01), Burlingame et al.

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