Process for producing .alpha.-(tert-Alkyl) cyanoacetic acid este

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitriles

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C07C25535

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057263426

ABSTRACT:
There is provide an advantageous process for producing an .alpha.-(tert-alkyl)cyanoacetic acid ester characterized by reacting cyanoacetic acid ester with a di(lower alkyl)aluminum halide, and then reacting the resulting reaction with a tert-alkyl halide.

REFERENCES:
Liebig.Ann.Chem.718, 101-114 (1968) "Direckte tert.-Alkylierung CH-acider Verbindungen" von Peter Boldt.
J.Am. Chem. Soc.92, (1970), pp. 4132-4133, "Rearrangememt of Azidoquinones.VII.Thermal Cleavage of 2,5-Diazidoquinones to Cyanoketenes. Syntheses of t-Butylycyanoketene" James V. Beitz et al.
J.Am.Chem.Soc. 72 (1950) "A Synthesis of Ethyl t-Alkylcyanoacetates" Elliot R. Alexander et al. pp. 4791-4792.

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