Process for producing .alpha.-l-aspartyldipeptide amide derivati

Details Process for producing .alpha.-l-aspartyldipeptide amide derivati Process for producing .alpha.-l-aspartyldipeptide amide derivati

1995-12-28

1998-03-03

Kumar, Shailendra

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 41, 560142, 560144, 560145, 549 76, 549493, 549434, 546329, 546333, 426548, 558414, C07C22900

Patent

active

057236518

ABSTRACT:
An economical process for producing .alpha.-L-aspartyldipeptide amide derivatives useful as sweeteners, by using amino protecting groups which can be removed by hydrolysis under acidic conditions, resulting in conversion of a .beta.-carboxyl acid ester to a carboxylic acid.

REFERENCES:
patent: 4411925 (1983-10-01), Brennan et al.
The Chemical Synthesis of Peptides, pp. 49-51, 1991, John Jones, "Activation and Coupling of Amino Acid Derivatives".
Chemical Abstracts, vol. 108, No. 13, AN 112959z, Mar. 28, 1988.

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