Process for producing alpha-L-aspartyl-L-phenylalanine methyl es

Details Process for producing alpha-L-aspartyl-L-phenylalanine methyl es Process for producing alpha-L-aspartyl-L-phenylalanine methyl es

1987-08-11

1989-05-16

Gray, Bruce D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C07C10102

Patent

active

048311804

ABSTRACT:
A process for producing dry .alpha.-L-aspartyl-L-phenylalanine methyl ester having an improved solubility by drying wet crystals of .alpha.-L-aspartyl-L-phenylalanine methyl ester, characterized in that the wet crystals of .alpha.-L-aspartyl-L-phenylalanine methyl ester are granulated so that the specific surface area during the drying operation is at least 4 m.sup.2 /g, followed by drying.

REFERENCES:
patent: 4579747 (1986-04-01), Sugiyama et al.
Perry et al, Chemical Engineers' Handbook, 5th ed., McGraw-Hill, New York, pp. 20-4 to 20-16 (1973).
"Application Potential For Aspartame in Low Calorie and Dietetic Foods", In Low Calorie and Special Dietary Foods, pp. 59-114, CRC Press 1978 CRF 21, Food and Drugs Revised as of Apr. 1, 1981.

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