Process for producing alicyclic aldehydes

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

Reexamination Certificate

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C568S443000

Reexamination Certificate

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07071362

ABSTRACT:
In the production of an alicyclic aldehyde, a starting aromatic aldehyde is converted into an aromatic acetal for protecting the formyl group. The aromatic ring of the aromatic acetal is then hydrogenated to convert the aromatic acetal into an alicyclic acetal, which is then hydrolyzed to cleave the acetal protecting group to obtain the aimed alicyclic aldehyde.

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Sulzbacher, et al. “The Preparation of Some Cyclic Acetals”, J. Am. Chem. Soc., vol. 70, No. 8, 1948, pp. 2827-2828.
Martin, et al., “Halogenated Carbonyl Ylides in the Reactions of Mercurial Dihalocarbene Precursors with Substituted Benzaldehydes”, J. Org. Chem. vol. 43, No. 6, 1978, pp. 1071-1076.
Nielsen, et al., “Synthesis of 3,5,12-Triazawurtzitanes (3,5,12-Triazatetracyclo[5.3.1.12,0.04,9]dodecanes)”, J. Org. Chem., 1987, vol. 52, No. 9, pp. 1656-1662.
Marconi, et al., “Nanostructured ruthenium on y-Al2O3catalysts for the efficient hydrogenation of aromatic compounds”, Journal of Organometallic Chemistry 689 (2004), pp. 639-646.

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