Process for producing albumin preparation

Details Process for producing albumin preparation Process for producing albumin preparation

1995-06-01

1997-04-01

Nutter, Nathan M.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Albumin

530416, 530417, 210263, 210290, 210660, 210661, 210663, 210679, C07K 322

Patent

active

056166915

ABSTRACT:
The process for producing the albumin preparation of the present invention comprises treating an aqueous albumin solution with an anion exchanger and a cation exchanger and subjecting the solution to heat treatment wherein a polyacrylamide type carrier having a cation exchange group is used as a cation exchanger. By using a polyacrylamide type carrier as a cation exchanger, the polymerization caused by the contaminating proteins can be suppressed, and a highly purified albumin preparation can be obtained.

REFERENCES:
patent: 4043997 (1977-08-01), Schroeder
patent: 4075197 (1978-02-01), Schuck et al.
patent: 4086222 (1978-04-01), Lindquist et al.
patent: 4228154 (1980-10-01), Fisher et al.
patent: 5277818 (1994-01-01), Matsuoka et al.
Purification Chromatograhique de l'albumine plastique humaine a l'echelle pilote, 1987, pp. 103-106.
9-Biochem Methods, vol. 108, 1988, pp. 283 Abstract 108:218559j.

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